
You open your blood test results and see:
HbA1c: 42 mmol/mol.
Or perhaps yours says:
HbA1c: 6.0%.
Okay... but what does that actually mean?
If nobody has explained HbA1c to you before, the number itself isn't particularly helpful. You may wonder whether it's high, whether it means you have diabetes, why somebody else's result is written as a percentage, or why your HbA1c doesn't seem to match the glucose readings you've been seeing at home.
HbA1c is one of the most commonly used measurements in diabetes care. It can help with diagnosing type 2 diabetes and is also used to monitor glucose levels over time in people who already have diabetes.
But it is not a perfect summary of everything happening with your blood glucose.
So, let's unpack what this number actually tells you — and what it doesn't.
HbA1c, also known as A1C or glycated haemoglobin, is a blood test that gives an indication of your glucose levels over approximately the previous two to three months.
To understand how it works, we need to talk briefly about your red blood cells.
Inside red blood cells is a protein called haemoglobin. Its main job is to help carry oxygen around your body.
As glucose circulates in your bloodstream, some of it naturally attaches to haemoglobin, creating a specific type of hemoglobin called glycated haemoglobin (HbA1c). The HbA1c test measures the proportion of haemoglobin that has glucose attached to it.
Generally, the more glucose that has been circulating in your blood over time, the higher your HbA1c will be.
That's why HbA1c can give your healthcare team information that a single glucose reading cannot.
You've probably heard HbA1c described as your “three-month average blood sugar.”
That's useful as a simple explanation, but it isn't quite the whole story.
HbA1c reflects glucose exposure over roughly the previous two to three months. However, it doesn't give every day in that period exactly the same influence.
More recent glucose levels contribute more to the result than glucose levels from further back.
So rather than thinking of HbA1c as a perfect mathematical average of every glucose reading you've had for three months, think of it as a longer-term picture of your recent glucose exposure.
That distinction becomes particularly useful when you're trying to understand why an HbA1c result has changed.
Here's a simple way to think about it:
A glucose reading is a snapshot.
HbA1c is the bigger picture.
If you check your glucose with a meter, you're seeing your glucose level around that particular moment.
That number can change throughout the day depending on factors such as meals, physical activity, medication, illness and other influences.
HbA1c looks across a much longer period.
That means you could check your glucose one morning and get a perfectly reasonable result while still having an elevated HbA1c.
It also works the other way around: one unusually high glucose reading doesn't necessarily tell you what your glucose has been doing over several months.
The two measurements provide different pieces of information.
Now for the part that causes completely unnecessary confusion.
You may see an HbA1c result written like this:
6.5%
While someone else has:
48 mmol/mol
These aren't two different tests.
They're two different ways of reporting HbA1c.
The percentage system is commonly associated with the NGSP reporting system, while mmol/mol is the IFCC unit widely used in places including the UK.

So if one resource talks about 6.5% and another talks about 48 mmol/mol, they're describing approximately the same HbA1c level.
The NGSP provides standardised conversion between HbA1c reporting systems.
For nonpregnant adults, an HbA1c of 6.5% (48 mmol/mol) or higher meets the HbA1c laboratory threshold used to diagnose diabetes.
Under ADA criteria:
But there's an important distinction between being in the diabetes range and having a diagnosis confirmed.
If there isn't unequivocal hyperglycaemia, diagnosis requires confirmation. This can involve another abnormal result from the same test at a different time or an abnormal result from a different diagnostic test.
We've explored that in much more detail in our guide:
How Is Type 2 Diabetes Diagnosed? Understanding HbA1c, Fasting Glucose and More
No.
One advantage of HbA1c is that you don't need to fast beforehand.
Unlike a fasting plasma glucose test, which requires at least eight hours without caloric intake, an HbA1c blood sample can generally be taken without planning your meal around the appointment.
So yes, you can have breakfast before an HbA1c test.
This is where the answer becomes more personal.
There isn't one HbA1c target that's right for every person with diabetes.
For many nonpregnant adults with diabetes, the ADA recommends an HbA1c goal of less than 7% (53 mmol/mol) provided this can be achieved without severe hypoglycaemia or hypoglycaemia that negatively affects health or quality of life.
But that doesn't mean everybody with diabetes should chase exactly the same number.
HbA1c goals should be individualised. Factors such as overall health, other medical conditions, risk of hypoglycaemia, treatment burden and personal circumstances can influence the most appropriate target. In some circumstances a lower target may be reasonable, while in others a less stringent target may be safer and more appropriate.
And there's a distinction here that's easy to miss:
6.5% (48 mmol/mol) is a diagnostic threshold.
Less than 7% (53 mmol/mol) is a common treatment goal for many adults who already have diabetes.
Those numbers are used for different purposes.
Not necessarily.
It can be tempting to think:
If a lower HbA1c is good, an even lower one must be better.
Diabetes management isn't quite that simple.
The aim is to maintain glucose at a level that reduces the risk of complications while avoiding unnecessary treatment harms, particularly hypoglycaemia in people using treatments that can cause it.
The ADA therefore recommends individualising glucose goals rather than pursuing the lowest HbA1c possible for everyone.
Your HbA1c isn't a score.
And diabetes management isn't a competition to see who can produce the smallest number.
This is a very reasonable question.
Perhaps your HbA1c is higher than you expected, yet whenever you check your glucose at home, the numbers don't look particularly high.
There are several possible reasons.
First, a handful of finger-prick readings represents only a tiny fraction of everything your glucose has been doing over weeks and months.
If you usually check at similar times, perhaps first thing in the morning, you may not be seeing what happens at other times of day.
Second, HbA1c and glucose measurements are simply different measurements.
And third, there are circumstances in which HbA1c itself may not accurately reflect glucose exposure.
In fact, the ADA recommends investigating consistent, substantial differences between measured glucose and HbA1c rather than simply assuming one of them should be ignored.
This is one of the most important limitations of HbA1c.
Remember that the test depends on haemoglobin inside red blood cells.
Anything that significantly changes your red blood cells, their lifespan or certain forms of haemoglobin can potentially change how an HbA1c result should be interpreted.
Examples include some haemoglobin variants and conditions that alter red-cell turnover. Recent significant blood loss, haemolytic anaemia, blood transfusion, erythropoietin treatment and haemodialysis are among situations that can affect HbA1c results. Iron-deficiency anaemia can also affect results.
Importantly, these factors don't all affect HbA1c in the same direction.
Some can make the result appear lower than expected, while others may make it appear higher.
Certain haemoglobin variants can also interfere with particular laboratory HbA1c methods, which is why the specific testing method can matter.
The ADA recommends using plasma glucose criteria for diagnosing diabetes in situations where the relationship between HbA1c and glucose is altered.
So if an HbA1c result seems completely out of step with everything else, that's something to discuss with your healthcare professional rather than trying to make the numbers fit yourself.
Not individually.
Imagine two people who have the same HbA1c.
Their day-to-day glucose patterns could still look quite different.
One might have relatively steady glucose levels.
The other might experience larger rises and falls but end up with a similar overall HbA1c.
HbA1c alone cannot tell you exactly:
what happens after individual meals
That's one reason HbA1c shouldn't be thought of as the entire story of glucose management.
Depending on the person and their treatment, finger-prick monitoring or continuous glucose monitoring can provide additional information that HbA1c simply cannot show.
There isn't one testing schedule for everyone.
How often HbA1c needs to be measured depends partly on whether glucose goals are being met and whether treatment has recently changed.
People whose glucose management is stable and within their individual goals may need HbA1c checked less frequently, while more frequent assessment can be useful when treatment is changing or glucose goals aren't being met.
Your healthcare team can determine an appropriate schedule based on your circumstances.
You may sometimes see something called estimated average glucose, or eAG, alongside your HbA1c.
eAG converts HbA1c into glucose units that may look more familiar if you use a glucose meter.
But there's an important word in the name:
estimated.
Your eAG isn't a prediction of what your glucose meter should display every time you check.
It's an estimate derived from the relationship between HbA1c and average glucose. Your individual glucose readings will naturally move above and below it.
First, don't panic over a number without understanding what it means in your circumstances.
Whether an HbA1c is considered high. and what should happen next, depends on why the test was performed.
If you're being investigated for possible diabetes, an HbA1c in the diabetes range may require confirmatory testing depending on the clinical situation.
If you already have diabetes, the question is different. Your result can be considered alongside your individual glucose target, medications, glucose-monitoring information and wider health.
Rather than looking at HbA1c as a pass-or-fail grade, it can be more useful to ask:
What has changed?
Does this result fit with my other glucose information?
Is my current treatment plan working for me?
Is there anything practical that needs adjusting?
Those are much more useful questions than simply labelling yourself as having a “good” or “bad” HbA1c.
HbA1c takes something complicated... months of changing glucose levels, and condenses it into one useful number.
That's its strength.
But it's also its limitation.
One number cannot show every glucose rise, every low, every meal response or every hour of your day. And in some medical circumstances, HbA1c may not accurately represent glucose exposure at all.
So when your next result arrives, don't look at it simply as:
42.
48.
53.
Look at what the number is telling you in context.
Because the most useful question isn't:
“Is this number good or bad?”
It's:
“What does this number mean for me and what should I do with that information?”
HbA1c refers to glycated haemoglobin... haemoglobin in red blood cells that has glucose attached to it. The test is also commonly called A1C or haemoglobin A1c.
No. A glucose test measures glucose at a particular time, while HbA1c provides information about glucose exposure over approximately the previous two to three months.
An HbA1c of 48 mmol/mol (6.5%) or above is in the diabetes diagnostic range. However, in the absence of unequivocal hyperglycaemia, diagnosis requires confirmation.
No. HbA1c testing doesn't require fasting.
An HbA1c goal below 7% (53 mmol/mol) is appropriate for many nonpregnant adults with diabetes, but individual targets can be higher or lower depending on the person's circumstances.
HbA1c is a useful clinical test, but certain haemoglobin variants and conditions affecting red blood cells can cause the result to differ from actual glucose exposure. An unexpected result should therefore be interpreted in clinical context.
American Diabetes Association Professional Practice Committee. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes—2026. Diabetes Care.
American Diabetes Association Professional Practice Committee. Glycemic Goals, Hypoglycemia, and Hyperglycemic Crises: Standards of Care in Diabetes—2026. Diabetes Care.
National Institute of Diabetes and Digestive and Kidney Diseases. The A1C Test & Diabetes.
National Glycohemoglobin Standardization Program. Factors that Interfere with HbA1c Test Results. Updated June 2026.

About The Author
Abigael Kuponiyi MSc, is a Clinical Exercise Physiologist, public health researcher and diabetes educator specialising in evidence-based lifestyle medicine.
👉 Explore free guides and tools at InstaHealthBlog.com